A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in Fasciola hepatica Carboxylesterase B

Fasciola hepatica anthelmintic resistance may be associated with the catalytic activity of xenobiotic metabolizing enzymes. The gene expression of one of these enzymes, identified as carboxylesterase B (CestB), was previously described as inducible in adult parasites under anthelmintic treatment and...

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Detalles Bibliográficos
Autores principales: Miranda-Miranda, Estefan, Scarcella, Silvana, Reynaud, Enrique, Narváez-Padilla, Verónica, Neira, Gisela, Mera-y-Sierra, Roberto, Aguilar-Díaz, Hugo, Cossio-Bayugar, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601742/
https://www.ncbi.nlm.nih.gov/pubmed/36292784
http://dx.doi.org/10.3390/genes13101899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601742/
https://www.ncbi.nlm.nih.gov/pubmed/36292784
http://dx.doi.org/10.3390/genes13101899

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