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A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in Fasciola hepatica Carboxylesterase B
Fasciola hepatica anthelmintic resistance may be associated with the catalytic activity of xenobiotic metabolizing enzymes. The gene expression of one of these enzymes, identified as carboxylesterase B (CestB), was previously described as inducible in adult parasites under anthelmintic treatment and...
Autores principales: | Miranda-Miranda, Estefan, Scarcella, Silvana, Reynaud, Enrique, Narváez-Padilla, Verónica, Neira, Gisela, Mera-y-Sierra, Roberto, Aguilar-Díaz, Hugo, Cossio-Bayugar, Raquel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601742/ https://www.ncbi.nlm.nih.gov/pubmed/36292784 http://dx.doi.org/10.3390/genes13101899 |
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