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Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19
Cereals have phytochemical compounds that can diminish the incidence of chronic diseases such as hypertension. The angiotensin-converting enzyme 2 (ACE2) participates in the modulation of blood pressure and is the principal receptor of the virus SARS-CoV-2. The inhibitors of the angiotensin-converti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601750/ https://www.ncbi.nlm.nih.gov/pubmed/37430980 http://dx.doi.org/10.3390/foods11203231 |
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author | García-Castro, Abigail Román-Gutiérrez, Alma Delia Castañeda-Ovando, Araceli Cariño-Cortés, Raquel Acevedo-Sandoval, Otilio Arturo López-Perea, Patricia Guzmán-Ortiz, Fabiola Araceli |
author_facet | García-Castro, Abigail Román-Gutiérrez, Alma Delia Castañeda-Ovando, Araceli Cariño-Cortés, Raquel Acevedo-Sandoval, Otilio Arturo López-Perea, Patricia Guzmán-Ortiz, Fabiola Araceli |
author_sort | García-Castro, Abigail |
collection | PubMed |
description | Cereals have phytochemical compounds that can diminish the incidence of chronic diseases such as hypertension. The angiotensin-converting enzyme 2 (ACE2) participates in the modulation of blood pressure and is the principal receptor of the virus SARS-CoV-2. The inhibitors of the angiotensin-converting enzyme (ACE) and the block receptors of angiotensin II regulate the expression of ACE2; thus, they could be useful in the treatment of patients infected with SARS-CoV-2. The inferior peptides from 1 to 3 kDa and the hydrophobic amino acids are the best candidates to inhibit ACE, and these compounds are present in rice, corn, wheat, oats, sorghum, and barley. In addition, the vitamins C and E, phenolic acids, and flavonoids present in cereals show a reduction in the oxidative stress involved in the pathogenesis of hypertension. The influence of ACE on hypertension and COVID-19 has turned into a primary point of control and treatment from the nutritional perspective. The objective of this work was to describe the inhibitory effect of the angiotensin-converting enzyme that the bioactive compounds present in cereals possess in order to lower blood pressure and how their consumption could be associated with reducing the virulence of COVID-19. |
format | Online Article Text |
id | pubmed-9601750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96017502022-10-27 Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19 García-Castro, Abigail Román-Gutiérrez, Alma Delia Castañeda-Ovando, Araceli Cariño-Cortés, Raquel Acevedo-Sandoval, Otilio Arturo López-Perea, Patricia Guzmán-Ortiz, Fabiola Araceli Foods Review Cereals have phytochemical compounds that can diminish the incidence of chronic diseases such as hypertension. The angiotensin-converting enzyme 2 (ACE2) participates in the modulation of blood pressure and is the principal receptor of the virus SARS-CoV-2. The inhibitors of the angiotensin-converting enzyme (ACE) and the block receptors of angiotensin II regulate the expression of ACE2; thus, they could be useful in the treatment of patients infected with SARS-CoV-2. The inferior peptides from 1 to 3 kDa and the hydrophobic amino acids are the best candidates to inhibit ACE, and these compounds are present in rice, corn, wheat, oats, sorghum, and barley. In addition, the vitamins C and E, phenolic acids, and flavonoids present in cereals show a reduction in the oxidative stress involved in the pathogenesis of hypertension. The influence of ACE on hypertension and COVID-19 has turned into a primary point of control and treatment from the nutritional perspective. The objective of this work was to describe the inhibitory effect of the angiotensin-converting enzyme that the bioactive compounds present in cereals possess in order to lower blood pressure and how their consumption could be associated with reducing the virulence of COVID-19. MDPI 2022-10-16 /pmc/articles/PMC9601750/ /pubmed/37430980 http://dx.doi.org/10.3390/foods11203231 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review García-Castro, Abigail Román-Gutiérrez, Alma Delia Castañeda-Ovando, Araceli Cariño-Cortés, Raquel Acevedo-Sandoval, Otilio Arturo López-Perea, Patricia Guzmán-Ortiz, Fabiola Araceli Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19 |
title | Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19 |
title_full | Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19 |
title_fullStr | Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19 |
title_full_unstemmed | Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19 |
title_short | Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19 |
title_sort | cereals as a source of bioactive compounds with anti-hypertensive activity and their intake in times of covid-19 |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601750/ https://www.ncbi.nlm.nih.gov/pubmed/37430980 http://dx.doi.org/10.3390/foods11203231 |
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