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Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19

Cereals have phytochemical compounds that can diminish the incidence of chronic diseases such as hypertension. The angiotensin-converting enzyme 2 (ACE2) participates in the modulation of blood pressure and is the principal receptor of the virus SARS-CoV-2. The inhibitors of the angiotensin-converti...

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Autores principales: García-Castro, Abigail, Román-Gutiérrez, Alma Delia, Castañeda-Ovando, Araceli, Cariño-Cortés, Raquel, Acevedo-Sandoval, Otilio Arturo, López-Perea, Patricia, Guzmán-Ortiz, Fabiola Araceli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601750/
https://www.ncbi.nlm.nih.gov/pubmed/37430980
http://dx.doi.org/10.3390/foods11203231
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author García-Castro, Abigail
Román-Gutiérrez, Alma Delia
Castañeda-Ovando, Araceli
Cariño-Cortés, Raquel
Acevedo-Sandoval, Otilio Arturo
López-Perea, Patricia
Guzmán-Ortiz, Fabiola Araceli
author_facet García-Castro, Abigail
Román-Gutiérrez, Alma Delia
Castañeda-Ovando, Araceli
Cariño-Cortés, Raquel
Acevedo-Sandoval, Otilio Arturo
López-Perea, Patricia
Guzmán-Ortiz, Fabiola Araceli
author_sort García-Castro, Abigail
collection PubMed
description Cereals have phytochemical compounds that can diminish the incidence of chronic diseases such as hypertension. The angiotensin-converting enzyme 2 (ACE2) participates in the modulation of blood pressure and is the principal receptor of the virus SARS-CoV-2. The inhibitors of the angiotensin-converting enzyme (ACE) and the block receptors of angiotensin II regulate the expression of ACE2; thus, they could be useful in the treatment of patients infected with SARS-CoV-2. The inferior peptides from 1 to 3 kDa and the hydrophobic amino acids are the best candidates to inhibit ACE, and these compounds are present in rice, corn, wheat, oats, sorghum, and barley. In addition, the vitamins C and E, phenolic acids, and flavonoids present in cereals show a reduction in the oxidative stress involved in the pathogenesis of hypertension. The influence of ACE on hypertension and COVID-19 has turned into a primary point of control and treatment from the nutritional perspective. The objective of this work was to describe the inhibitory effect of the angiotensin-converting enzyme that the bioactive compounds present in cereals possess in order to lower blood pressure and how their consumption could be associated with reducing the virulence of COVID-19.
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spelling pubmed-96017502022-10-27 Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19 García-Castro, Abigail Román-Gutiérrez, Alma Delia Castañeda-Ovando, Araceli Cariño-Cortés, Raquel Acevedo-Sandoval, Otilio Arturo López-Perea, Patricia Guzmán-Ortiz, Fabiola Araceli Foods Review Cereals have phytochemical compounds that can diminish the incidence of chronic diseases such as hypertension. The angiotensin-converting enzyme 2 (ACE2) participates in the modulation of blood pressure and is the principal receptor of the virus SARS-CoV-2. The inhibitors of the angiotensin-converting enzyme (ACE) and the block receptors of angiotensin II regulate the expression of ACE2; thus, they could be useful in the treatment of patients infected with SARS-CoV-2. The inferior peptides from 1 to 3 kDa and the hydrophobic amino acids are the best candidates to inhibit ACE, and these compounds are present in rice, corn, wheat, oats, sorghum, and barley. In addition, the vitamins C and E, phenolic acids, and flavonoids present in cereals show a reduction in the oxidative stress involved in the pathogenesis of hypertension. The influence of ACE on hypertension and COVID-19 has turned into a primary point of control and treatment from the nutritional perspective. The objective of this work was to describe the inhibitory effect of the angiotensin-converting enzyme that the bioactive compounds present in cereals possess in order to lower blood pressure and how their consumption could be associated with reducing the virulence of COVID-19. MDPI 2022-10-16 /pmc/articles/PMC9601750/ /pubmed/37430980 http://dx.doi.org/10.3390/foods11203231 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
García-Castro, Abigail
Román-Gutiérrez, Alma Delia
Castañeda-Ovando, Araceli
Cariño-Cortés, Raquel
Acevedo-Sandoval, Otilio Arturo
López-Perea, Patricia
Guzmán-Ortiz, Fabiola Araceli
Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19
title Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19
title_full Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19
title_fullStr Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19
title_full_unstemmed Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19
title_short Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19
title_sort cereals as a source of bioactive compounds with anti-hypertensive activity and their intake in times of covid-19
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601750/
https://www.ncbi.nlm.nih.gov/pubmed/37430980
http://dx.doi.org/10.3390/foods11203231
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