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Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3

The camelid single domain antibody, referred to VHH or Nanobody, is considered a versatile tool for various biotechnological and clinical applications because of its favorable biophysical properties. To take advantage of these characteristics and for its application in biotechnology and therapy, res...

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Detalles Bibliográficos
Autores principales:	Kinoshita, Seisho, Nakakido, Makoto, Mori, Chinatsu, Kuroda, Daisuke, Caaveiro, Jose M.M., Tsumoto, Kouhei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Full‐length Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601775/ https://www.ncbi.nlm.nih.gov/pubmed/36153698 http://dx.doi.org/10.1002/pro.4450

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