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HDAC4 depletion ameliorates IL‐13‐triggered inflammatory response and mucus production in nasal epithelial cells via activation of SIRT1/NF‐κB signaling

INTRODUCTION: Allergic rhinitis (AR) is frequently known as a chronic respiratory disease with a global high prevalence. The pivotal roles of histone deacetylase 4 (HDAC4) in multiple human diseases have been underlined by numerous studies. Nevertheless, whether HDAC4 is implicated in AR remains to...

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Detalles Bibliográficos
Autores principales: Xu, Hangyu, Wang, Lingjun, Chen, Huaqun, Cai, Hefei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601864/
https://www.ncbi.nlm.nih.gov/pubmed/36301023
http://dx.doi.org/10.1002/iid3.692