Design and optimization of enzymatic activity in a de novo β‐barrel scaffold

While native scaffolds offer a large diversity of shapes and topologies for enzyme engineering, their often unpredictable behavior in response to sequence modification makes de novo generated scaffolds an exciting alternative. Here we explore the customization of the backbone and sequence of a de no...

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Detalles Bibliográficos
Autores principales: Kipnis, Yakov, Chaib, Anissa Ouald, Vorobieva, Anastassia A., Cai, Guangyang, Reggiano, Gabriella, Basanta, Benjamin, Kumar, Eshan, Mittl, Peer R.E., Hilvert, Donald, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601869/
https://www.ncbi.nlm.nih.gov/pubmed/36305767
http://dx.doi.org/10.1002/pro.4405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9601869/
https://www.ncbi.nlm.nih.gov/pubmed/36305767
http://dx.doi.org/10.1002/pro.4405

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