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The Selection of Antibiotic- and Bacteriophage-Resistant Pseudomonas aeruginosa Is Prevented by Their Combination

Bacteria developing resistance compromise the efficacy of antibiotics or bacteriophages (phages). We tested the association of these two antibacterials to circumvent resistance. With the Hollow Fiber Infection Model (HFIM), we mimicked the concentration profile of ciprofloxacin in the lungs of patie...

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Detalles Bibliográficos
Autores principales: Ferran, Aude A., Lacroix, Marlène Z., Gourbeyre, Ophélie, Huesca, Alicia, Gaborieau, Baptiste, Debarbieux, Laurent, Bousquet-Mélou, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602269/
https://www.ncbi.nlm.nih.gov/pubmed/36135376
http://dx.doi.org/10.1128/spectrum.02874-22