Mechanisms of IS26-Mediated Amplification of the aphA1 Gene Leading to Tobramycin Resistance in an Acinetobacter baumannii Isolate

Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic resistance gene that impact therapeutic options are increasingly observed. Amplification can also disclose novel phenotypes leading to treatment failure. However, the mechanism is poorly understood. Here, the ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Harmer, Christopher J., Lebreton, Francois, Stam, Jason, McGann, Patrick T., Hall, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602291/
https://www.ncbi.nlm.nih.gov/pubmed/36073931
http://dx.doi.org/10.1128/spectrum.02287-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602291/
https://www.ncbi.nlm.nih.gov/pubmed/36073931
http://dx.doi.org/10.1128/spectrum.02287-22

Ejemplares similares