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Repair Foci as Liquid Phase Separation: Evidence and Limitations

In response to DNA double strand breaks (DSB), repair proteins accumulate at damaged sites, forming membrane-less condensates or “foci”. The formation of these foci and their disassembly within the proper time window are essential for genome integrity. However, how these membrane-less sub-compartmen...

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Detalles Bibliográficos
Autores principales: Miné-Hattab, Judith, Liu, Siyu, Taddei, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602295/
https://www.ncbi.nlm.nih.gov/pubmed/36292731
http://dx.doi.org/10.3390/genes13101846