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GRANT Motif Regulates CENP-A Incorporation and Restricts RNA Polymerase II Accessibility at Centromere

Precise chromosome segregation is essential for maintaining genomic stability, and its proper execution centers on the centromere, a chromosomal locus that mounts the kinetochore complex to mediate attachment of chromosomes to the spindle microtubules. The location of the centromere is epigeneticall...

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Detalles Bibliográficos
Autores principales: Tan, Hwei Ling, Chen, Ee Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602348/
https://www.ncbi.nlm.nih.gov/pubmed/36292582
http://dx.doi.org/10.3390/genes13101697