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Altered Circulating Follicular T Helper Cell Subsets and Follicular T Regulatory Cells Are Indicators of a Derailed B Cell Response in Lupus, Which Could Be Modified by Targeting IL-21R

Systemic lupus erythematosus (SLE) is characterized by the breakdown of self-tolerance, the production of high-affinity pathogenic autoantibodies and derailed B cell responses, which indicates the importance of central players, such as follicular T helper (T(FH)) subsets and follicular T regulatory...

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Detalles Bibliográficos
Autores principales: Szabó, Krisztina, Jámbor, Ilona, Pázmándi, Kitti, Nagy, Nikolett, Papp, Gábor, Tarr, Tünde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602506/
https://www.ncbi.nlm.nih.gov/pubmed/36293075
http://dx.doi.org/10.3390/ijms232012209