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Altered Circulating Follicular T Helper Cell Subsets and Follicular T Regulatory Cells Are Indicators of a Derailed B Cell Response in Lupus, Which Could Be Modified by Targeting IL-21R
Systemic lupus erythematosus (SLE) is characterized by the breakdown of self-tolerance, the production of high-affinity pathogenic autoantibodies and derailed B cell responses, which indicates the importance of central players, such as follicular T helper (T(FH)) subsets and follicular T regulatory...
Autores principales: | Szabó, Krisztina, Jámbor, Ilona, Pázmándi, Kitti, Nagy, Nikolett, Papp, Gábor, Tarr, Tünde |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602506/ https://www.ncbi.nlm.nih.gov/pubmed/36293075 http://dx.doi.org/10.3390/ijms232012209 |
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