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The Anticancer Drug Bleomycin Shows Potent Antifungal Activity by Altering Phospholipid Biosynthesis

Invasive fungal infections are difficult to treat with limited drug options, mainly because fungi are eukaryotes and share many cellular mechanisms with the human host. Most current antifungal drugs are either fungistatic or highly toxic. Therefore, there is a critical need to identify important fun...

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Detalles Bibliográficos
Autores principales: Pokharel, Mona, Konarzewska, Paulina, Roberge, Jacques Y., Han, Gil-Soo, Wang, Yina, Carman, George M., Xue, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602507/
https://www.ncbi.nlm.nih.gov/pubmed/36036637
http://dx.doi.org/10.1128/spectrum.00862-22