Cargando…

Stem-Loop I of the Tembusu Virus 3′-Untranslated Region Is Responsible for Viral Host-Specific Adaptation and the Pathogenicity of the Virus in Mice

Tembusu virus (TMUV), an avian mosquito-borne flavivirus, was first identified from Culex tritaeniorhynchus in 1955. To validate the effects of the 3′-untranslated region (3′UTR) in viral host-specific adaptation, we generated a set of chimeric viruses using CQW1 (duck strain) and MM 1775 (mosquito...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Li, He, Yu, Wu, Zhen, Wang, Xiaoli, Guo, Jiaqi, Zhang, Senzhao, Wang, Mingshu, Jia, Renyong, Zhu, Dekang, Liu, Mafeng, Zhao, Xinxin, Yang, Qiao, Mao, Sai, Wu, Ying, Zhang, Shaqiu, Huang, Juan, Ou, Xumin, Gao, Qun, Sun, Di, Cheng, Anchun, Chen, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602528/
https://www.ncbi.nlm.nih.gov/pubmed/36214697
http://dx.doi.org/10.1128/spectrum.02449-22