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WNK1–OSR1 Signaling Regulates Angiogenesis-Mediated Metastasis towards Developing a Combinatorial Anti-Cancer Strategy

Lysine-deficient protein kinase-1 (WNK1) is critical for both embryonic angiogenesis and tumor-induced angiogenesis. However, the downstream effectors of WNK1 during these processes remain ambiguous. In this study, we identified that oxidative stress responsive 1b (osr1b) is upregulated in endotheli...

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Detalles Bibliográficos
Autores principales: Hou, Chia-Ying, Ma, Chung-Yung, Lin, Yu-Ju, Huang, Chou-Long, Wang, Horng-Dar, Yuh, Chiou-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602556/
https://www.ncbi.nlm.nih.gov/pubmed/36292952
http://dx.doi.org/10.3390/ijms232012100