Discovery of a Dual SENP1 and SENP2 Inhibitor

SUMOylation is a reversible post–translational modification (PTM) involving covalent attachment of small ubiquitin-related modifier (SUMO) proteins to substrate proteins. Dysregulation of SUMOylation and deSUMOylation results in cellular malfunction and is linked to various diseases, such as cancer....

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Detalles Bibliográficos
Autores principales: Brand, Michael, Bommeli, Elias Benjamin, Rütimann, Marc, Lindenmann, Urs, Riedl, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602571/
https://www.ncbi.nlm.nih.gov/pubmed/36292935
http://dx.doi.org/10.3390/ijms232012085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602571/
https://www.ncbi.nlm.nih.gov/pubmed/36292935
http://dx.doi.org/10.3390/ijms232012085

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