Production of Helvolic Acid in Metarhizium Contributes to Fungal Infection of Insects by Bacteriostatic Inhibition of the Host Cuticular Microbiomes

The nortriterpenoid helvolic acid (HA) has potent antibiotic activities and can be produced by different fungi, yet HA function remains elusive. Here, we report the chemical biology of HA production in the insect pathogen Metarhizium robertsii. After deletion of the core oxidosqualene cyclase gene i...

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Detalles Bibliográficos
Autores principales: Sun, Yanlei, Hong, Song, Chen, Haimin, Yin, Ying, Wang, Chengshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602595/
https://www.ncbi.nlm.nih.gov/pubmed/36047778
http://dx.doi.org/10.1128/spectrum.02620-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602595/
https://www.ncbi.nlm.nih.gov/pubmed/36047778
http://dx.doi.org/10.1128/spectrum.02620-22

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