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SARS-CoV-2 Variant Delta Potently Suppresses Innate Immune Response and Evades Interferon-Activated Antiviral Responses in Human Colon Epithelial Cells

The Delta variant of SARS-CoV-2 has caused more severe infections than its previous variants. We studied the host innate immune response to Delta, Alpha, and two earlier variants to map the evolution of the recent ones. Our biochemical and transcriptomic studies in human colon epithelial cell line C...

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Detalles Bibliográficos
Autores principales: Tandel, Dixit, Sah, Vishal, Singh, Nitesh Kumar, Potharaju, Poojitha Sai, Gupta, Divya, Shrivastava, Sauhard, Sowpati, Divya Tej, Harshan, Krishnan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602719/
https://www.ncbi.nlm.nih.gov/pubmed/36073824
http://dx.doi.org/10.1128/spectrum.01604-22