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Lipofuscin-Mediated Photic Stress Induces a Dark Toxic Effect on ARPE-19 Cells
Lipofuscin granules from retinal pigment epithelium (RPE) cells contain bisretinoid fluorophores, which are photosensitizers and are phototoxic to cells. In the presence of oxygen, bisretinoids are oxidized to form various products, containing aldehydes and ketones, which are also potentially cytoto...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9602730/ https://www.ncbi.nlm.nih.gov/pubmed/36293088 http://dx.doi.org/10.3390/ijms232012234 |