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Human Claudin-Derived Peptides Block the Membrane Fusion Process of Zika Virus and Are Broad Flavivirus Inhibitors

Zika virus (ZIKV) is a mosquito-borne flavivirus that emerged in the Pacific islands in 2007 and spread to the Americas in 2015. The infection remains asymptomatic in most cases but can be associated with severe neurological disorders. Despite massive efforts, no specific drug or vaccine against ZIK...

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Detalles Bibliográficos
Autores principales: Zoladek, Jim, Burlaud-Gaillard, Julien, Chazal, Maxime, Desgraupes, Sophie, Jeannin, Patricia, Gessain, Antoine, Pardigon, Nathalie, Hubert, Mathieu, Roingeard, Philippe, Jouvenet, Nolwenn, Afonso, Philippe V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603178/
https://www.ncbi.nlm.nih.gov/pubmed/36040168
http://dx.doi.org/10.1128/spectrum.02989-22