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RNA-Dependent RNA Polymerase of the Second Human Pegivirus Exhibits a High-Fidelity Feature

The virus-encoded RNA-dependent RNA polymerase (RdRp) is responsible for viral replication, and its fidelity is closely related to viral diversity, pathogenesis, virulence, and fitness. Hepatitis C virus (HCV) and the second human pegivirus (HPgV-2) belong to the family Flaviviridae and share some f...

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Detalles Bibliográficos
Autores principales: Chen, Shuyi, Wu, Jiqin, Yang, Xiaofeng, Sun, Qiuli, Liu, Su, Rashid, Farooq, Dzakah, Emmanuel Enoch, Wang, Haiying, Wang, Jufang, Gong, Peng, Tang, Shixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603181/
https://www.ncbi.nlm.nih.gov/pubmed/35980196
http://dx.doi.org/10.1128/spectrum.02729-22