Reduced Sensitivity of Commercial Spike-Specific Antibody Assays after Primary Infection with the SARS-CoV-2 Omicron Variant

The SARS-CoV-2 Omicron variant is characterized by substantial changes in the antigenic structure of the Spike (S) protein. Therefore, antibodies induced by primary Omicron infection lack neutralizing activity against earlier variants. In this study, we analyzed whether these antigenic changes impac...

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Detalles Bibliográficos
Autores principales: Springer, David Niklas, Perkmann, Thomas, Jani, Claudia Maria, Mucher, Patrick, Prüger, Katja, Marculescu, Rodrig, Reuberger, Elisabeth, Camp, Jeremy Vann, Graninger, Marianne, Borsodi, Christian, Deutsch, Josef, Lammel, Oliver, Aberle, Stephan Walter, Puchhammer-Stöckl, Elisabeth, Haslacher, Helmuth, Höltl, Eva, Aberle, Judith Helene, Stiasny, Karin, Weseslindtner, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603218/
https://www.ncbi.nlm.nih.gov/pubmed/36005839
http://dx.doi.org/10.1128/spectrum.02129-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603218/
https://www.ncbi.nlm.nih.gov/pubmed/36005839
http://dx.doi.org/10.1128/spectrum.02129-22

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