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B.1.351 SARS-CoV-2 Variant Exhibits Higher Virulence but Less Viral Shedding than That of the Ancestral Strain in Young Nonhuman Primates

We investigated the distribution, virulence, and pathogenic characteristics of mutated SARS-CoV-2 to clarify the association between virulence and the viral spreading ability of current and future circulating strains. Chinese rhesus macaques were infected with ancestral SARS-CoV-2 strain GD108 and B...

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Detalles Bibliográficos
Autores principales: Bai, Yu, He, Qian, Yang, Jinghuan, Lu, Shuaiyao, Mao, Qunying, Gao, Fan, Bian, Lianlian, Zhang, Jialu, An, Chaoqiang, Liu, Jianyang, Wu, Xing, Yu, Wenhai, Wang, Zhongfang, Peng, Xiaozhong, Wang, Junzhi, Liang, Zhenglun, Xu, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603226/
https://www.ncbi.nlm.nih.gov/pubmed/36069561
http://dx.doi.org/10.1128/spectrum.02263-22