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Dysregulation of Placental Lipid Hydrolysis by High-Fat/High-Cholesterol Feeding and Gestational Diabetes Mellitus in Mice

Advanced maternal age and obesity are the main risk factors to develop gestational diabetes mellitus (GDM). Obesity is a consequence of the increased storage of triacylglycerol (TG). Cytosolic and lysosomal lipid hydrolases break down TG and cholesteryl esters (CE) to release fatty acids (FA), free...

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Detalles Bibliográficos
Autores principales: Kuentzel, Katharina B., Bradić, Ivan, Mihalič, Zala N., Korbelius, Melanie, Rainer, Silvia, Pirchheim, Anita, Kargl, Julia, Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603336/
https://www.ncbi.nlm.nih.gov/pubmed/36293139
http://dx.doi.org/10.3390/ijms232012286