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Single-Cell Transcriptomic Profiling in Inherited Retinal Degeneration Reveals Distinct Metabolic Pathways in Rod and Cone Photoreceptors

The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly understood. The aim of this study was to systematically map the transcriptional changes that occur in the degenerating mouse retina at the single cell level. To this end, we employed single-cell RNA-sequencing...

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Detalles Bibliográficos
Autores principales: Chen, Yiyi, Dong, Yujie, Yan, Jie, Wang, Lan, Yu, Shirley, Jiao, Kangwei, Paquet-Durand, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603353/
https://www.ncbi.nlm.nih.gov/pubmed/36293024
http://dx.doi.org/10.3390/ijms232012170