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Single-Cell Transcriptomic Profiling in Inherited Retinal Degeneration Reveals Distinct Metabolic Pathways in Rod and Cone Photoreceptors
The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly understood. The aim of this study was to systematically map the transcriptional changes that occur in the degenerating mouse retina at the single cell level. To this end, we employed single-cell RNA-sequencing...
Autores principales: | Chen, Yiyi, Dong, Yujie, Yan, Jie, Wang, Lan, Yu, Shirley, Jiao, Kangwei, Paquet-Durand, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603353/ https://www.ncbi.nlm.nih.gov/pubmed/36293024 http://dx.doi.org/10.3390/ijms232012170 |
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