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Biological Activity of Different Forms of Oxidized Parathyroid Hormone

Preclinical studies have shown that parathyroid hormone (PTH) loses its biological effects through oxidation. PTH can be oxidized at methionines 8 and 18. Three possible variations of oxidized PTH (oxPTH) exist: Met8(ox)PTH, Met18(ox)PTH, and Met8, Met18(di-ox)PTH. A recent study showed that Met18(o...

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Detalles Bibliográficos
Autores principales: Hasan, Ahmed A., Hocher, Carl-Friedrich, Kleuser, Burkhard, Krämer, Bernhard K., Hocher, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603367/
https://www.ncbi.nlm.nih.gov/pubmed/36293083
http://dx.doi.org/10.3390/ijms232012228