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Binding of Gamma-Glutamyl Transferase to TLR4 Signalling Allows Tissue Factor Activation in Monocytes

Gamma-glutamyl transferase (GGT) is involved in the progression of atherosclerosis, since its enzymatic activity promotes the generation of reactive oxygen species (ROS). Besides, GGT may act as a prothrombotic factor by inducing tissue factor (TF) expression, independently of its enzymatic activity...

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Detalles Bibliográficos
Autores principales: Sanguinetti, Chiara, Scalise, Valentina, Neri, Tommaso, Celi, Alessandro, Susini, Vanessa, Franzini, Maria, Pedrinelli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603380/
https://www.ncbi.nlm.nih.gov/pubmed/36293061
http://dx.doi.org/10.3390/ijms232012207