The Effect of Circumscribed Exposure to the Pan-Aurora Kinase Inhibitor VX-680 on Proliferating Euploid Cells

Small molecule inhibitors of aurora kinases are currently being investigated in oncology clinical trials. The long-term effects of these inhibitors on proliferating euploid cells have not been adequately studied. We examined the effect of the reversible pan-aurora kinase inhibitor VX-680 on p53-comp...

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Detalles Bibliográficos
Autores principales: Liu, Xumei, Shi, Qiong, Choudhry, Namrta, Zhang, Ting, Liu, Hong, Zhang, Shenqiu, Zhang, Jing, Yang, Dun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603438/
https://www.ncbi.nlm.nih.gov/pubmed/36292957
http://dx.doi.org/10.3390/ijms232012104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603438/
https://www.ncbi.nlm.nih.gov/pubmed/36292957
http://dx.doi.org/10.3390/ijms232012104

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