Background Filtering of Clinical Metagenomic Sequencing with a Library Concentration-Normalized Model

Metagenomic next-generation sequencing (mNGS) can accurately detect pathogens in clinical samples. However, wet-lab contamination constrains mNGS analysis and may result in erroneous interpretation of results. Many existing methods rely on large-scale observational microbiome studies and may not be...

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Detalles Bibliográficos
Autores principales: Du, Juan, Zhang, Jingjia, Zhang, Dong, Zhou, Yiwen, Wu, Pengfei, Ding, Wenchao, Wang, Jun, Ouyang, Chuan, Yang, Qiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Methods and Protocols
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603461/
https://www.ncbi.nlm.nih.gov/pubmed/36135379
http://dx.doi.org/10.1128/spectrum.01779-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603461/
https://www.ncbi.nlm.nih.gov/pubmed/36135379
http://dx.doi.org/10.1128/spectrum.01779-22

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