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Analysis of a Cell Wall Mutant Highlights Rho-Dependent Genome Amplification Events in Staphylococcus aureus

In a study of antibiotic resistance in Staphylococcus aureus, specific cell wall mutants were previously generated for the peptidoglycan biosynthesis gene murF, by the insertion of an integrative plasmid. A collection of 30 independent mutants was obtained, and all harbored a variable number of copi...

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Detalles Bibliográficos
Autores principales: Portela, Raquel, A. Faria, Nuno, Mwangi, Michael, Miragaia, Maria, de Lencastre, Hermínia, Tomasz, Alexander, Gonçalves Sobral, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603463/
https://www.ncbi.nlm.nih.gov/pubmed/36094182
http://dx.doi.org/10.1128/spectrum.02483-21