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Cytoskeleton Elements Contribute to Prion Peptide-Induced Endothelial Barrier Breakdown in a Blood–Brain Barrier In Vitro System
The mechanisms involved in the interaction of PrP 106-126, a peptide corresponding to the prion protein amyloidogenic region, with the blood–brain barrier (BBB) were studied. PrP 106-126 treatment that was previously shown to impair BBB function, reduced cAMP levels in cultured brain endothelial cel...
Autores principales: | Cooper, Itzik, Cohen-Kashi Malina, Katayun, Levin, Yishai, Gabashvili, Alexandra, Mohar, Boaz, Cagnotto, Alfredo, Salmona, Mario, Teichberg, Vivian I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603506/ https://www.ncbi.nlm.nih.gov/pubmed/36293002 http://dx.doi.org/10.3390/ijms232012126 |
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