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Phenotypical Flexibility of the EGFRvIII-Positive Glioblastoma Cell Line and the Multidirectional Influence of TGFβ and EGF on These Cells—EGFRvIII Appears as a Weak Oncogene

Background: The biological role of EGFRvIII (epidermal growth factor receptor variant three) remains unclear. Methods: Three glioblastoma DK-MG sublines were tested with EGF (epidermal growth factor) and TGFβ (transforming growth factor β). Sublines were characterized by an increased percentage of E...

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Detalles Bibliográficos
Autores principales: Włodarczyk, Aneta, Tręda, Cezary, Rutkowska, Adrianna, Grot, Dagmara, Dobrewa, Weronika, Kierasińska, Amelia, Węgierska, Marta, Wasiak, Tomasz, Strózik, Tadeusz, Rieske, Piotr, Stoczyńska-Fidelus, Ewelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603514/
https://www.ncbi.nlm.nih.gov/pubmed/36292985
http://dx.doi.org/10.3390/ijms232012129