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Possible Involvement of the Upregulation of ΔNp63 Expression Mediated by HER2-Activated Aryl Hydrocarbon Receptor in Mammosphere Maintenance

Cancer stem cells (CSCs) contribute to the drug resistance, recurrence, and metastasis of breast cancers. Recently, we demonstrated that HER2 overexpression increases mammosphere formation via the activation of aryl hydrocarbon receptor (AHR). In this study, the objective was to identify the mechani...

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Detalles Bibliográficos
Autores principales: Kanno, Yuichiro, Saito, Nao, Yamashita, Naoya, Ota, Kazuki, Shizu, Ryota, Hosaka, Takuomi, Nemoto, Kiyomitsu, Yoshinari, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603582/
https://www.ncbi.nlm.nih.gov/pubmed/36292946
http://dx.doi.org/10.3390/ijms232012095