Anti-PTK7 Monoclonal Antibodies Exhibit Anti-Tumor Activity at the Cellular Level and in Mouse Xenograft Models of Esophageal Squamous Cell Carcinoma

PTK7 is a catalytically defective receptor protein tyrosine kinase upregulated in various cancers, including esophageal squamous cell carcinoma (ESCC). In previous studies, we observed a positive correlation between PTK7 expression levels and tumorigenicity in various ESCC cell lines and xenograft m...

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Detalles Bibliográficos
Autores principales: Kim, Jae Hoon, Shin, Won-Sik, Lee, Se-Ra, Kim, Sanggil, Choi, So-Young, Lee, Seung-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603586/
https://www.ncbi.nlm.nih.gov/pubmed/36293051
http://dx.doi.org/10.3390/ijms232012195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603586/
https://www.ncbi.nlm.nih.gov/pubmed/36293051
http://dx.doi.org/10.3390/ijms232012195

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