Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump

Bacterial efflux pumps in the resistance-nodulation-cell division (RND) family of Gram-negative bacteria contribute significantly to the development of antimicrobial resistance by many pathogens. In this study, we selected the MtrD transporter protein of Neisseria gonorrhoeae as it is the sole RND p...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyu, Meinan, Ayala, Julio C., Chirakos, Isabella, Su, Chih-Chia, Shafer, William M., Yu, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603588/
https://www.ncbi.nlm.nih.gov/pubmed/36121287
http://dx.doi.org/10.1128/spectrum.02990-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603588/
https://www.ncbi.nlm.nih.gov/pubmed/36121287
http://dx.doi.org/10.1128/spectrum.02990-22

Ejemplares similares