Chalcone-Acridine Hybrid Suppresses Melanoma Cell Progression via G2/M Cell Cycle Arrest, DNA Damage, Apoptosis, and Modulation of MAP Kinases Activity

This study was focused on investigating the antiproliferative effects of chalcone hybrids in melanoma cancer cells. Among seven chalcone hybrids, the chalcone-acridine hybrid 1C was the most potent and was selected for further antiproliferative mechanism studies. This in vitro study revealed the pot...

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Detalles Bibliográficos
Autores principales: Gazdova, Maria, Michalkova, Radka, Kello, Martin, Vilkova, Maria, Kudlickova, Zuzana, Baloghova, Janette, Mirossay, Ladislav, Mojzis, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603750/
https://www.ncbi.nlm.nih.gov/pubmed/36293123
http://dx.doi.org/10.3390/ijms232012266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603750/
https://www.ncbi.nlm.nih.gov/pubmed/36293123
http://dx.doi.org/10.3390/ijms232012266

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