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Development of a Sensitive Screening Method for Simultaneous Determination of Nine Genotoxic Nitrosamines in Active Pharmaceutical Ingredients by GC-MS

A worldwide crisis with nitrosamine contamination in medical products began in 2018. Therefore, trace-level analysis of nitrosamines is becoming an emerging topic of interest in the field of quality control. A novel GC-MS method with electron ionization and microextraction was developed and validate...

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Detalles Bibliográficos
Autores principales: Witkowska, Anna B., Giebułtowicz, Joanna, Dąbrowska, Magdalena, Stolarczyk, Elżbieta U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603764/
https://www.ncbi.nlm.nih.gov/pubmed/36292981
http://dx.doi.org/10.3390/ijms232012125