Functional Characterization and Synthetic Application of Is2-SDR, a Novel Thermostable and Promiscuous Ketoreductase from a Hot Spring Metagenome

In a metagenome mining-based search of novel thermostable hydroxysteroid dehydrogenases (HSDHs), enzymes that are able to selectively oxidize/reduce steroidal compounds, a novel short-chain dehydrogenase/reductase (SDR), named Is2-SDR, was recently discovered. This enzyme, found in an Icelandic hot...

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Detalles Bibliográficos
Autores principales: Ferrandi, Erica Elisa, Bassanini, Ivan, Bertuletti, Susanna, Riva, Sergio, Tognoli, Chiara, Vanoni, Marta, Monti, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603792/
https://www.ncbi.nlm.nih.gov/pubmed/36293010
http://dx.doi.org/10.3390/ijms232012153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603792/
https://www.ncbi.nlm.nih.gov/pubmed/36293010
http://dx.doi.org/10.3390/ijms232012153

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