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Computational Modeling of Virally-encoded Ion Channel Structure
Viroporins are ion channels encoded within a virus’s genome, that facilitate a range of devastating infectious diseases such as COVID-19, HIV, and rotavirus. The non-structural protein 4 (NSP4) from rotavirus includes a viroporin domain that disrupts cellular Ca2+ homeostasis, initiating viral repli...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603836/ https://www.ncbi.nlm.nih.gov/pubmed/36299429 http://dx.doi.org/10.21203/rs.3.rs-2182743/v1 |