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Computational Modeling of Virally-encoded Ion Channel Structure

Viroporins are ion channels encoded within a virus’s genome, that facilitate a range of devastating infectious diseases such as COVID-19, HIV, and rotavirus. The non-structural protein 4 (NSP4) from rotavirus includes a viroporin domain that disrupts cellular Ca2+ homeostasis, initiating viral repli...

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Detalles Bibliográficos
Autores principales:	Weissman, Alexander, Bennett, Jeremy, Smith, Nicole, Burdorf, Carly, Johnston, Emma, Malachowsky, Beth, Banks, Lori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603836/ https://www.ncbi.nlm.nih.gov/pubmed/36299429 http://dx.doi.org/10.21203/rs.3.rs-2182743/v1

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