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Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-O-Methyltransferase

Catechol-O-methyltransferase (COMT) has been involved in a number of medical conditions including catechol-estrogen-induced cancers and a great range of cardiovascular and neurodegenerative diseases such as Parkinson’s disease. Currently, Parkinson’s disease treatment relies on a triple prophylaxis,...

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Detalles Bibliográficos
Autores principales: Gonçalves, Ana M., Pedro, Augusto Q., Oliveira, Diana M., Oliveira, Adriana E., Santos, Marino F. A., Correia, Márcia A. S., Queiroz, João A., Gallardo, Eugénia, Romão, Maria J., Passarinha, Luís A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603843/
https://www.ncbi.nlm.nih.gov/pubmed/36293152
http://dx.doi.org/10.3390/ijms232012298