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Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-O-Methyltransferase
Catechol-O-methyltransferase (COMT) has been involved in a number of medical conditions including catechol-estrogen-induced cancers and a great range of cardiovascular and neurodegenerative diseases such as Parkinson’s disease. Currently, Parkinson’s disease treatment relies on a triple prophylaxis,...
Autores principales: | Gonçalves, Ana M., Pedro, Augusto Q., Oliveira, Diana M., Oliveira, Adriana E., Santos, Marino F. A., Correia, Márcia A. S., Queiroz, João A., Gallardo, Eugénia, Romão, Maria J., Passarinha, Luís A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603843/ https://www.ncbi.nlm.nih.gov/pubmed/36293152 http://dx.doi.org/10.3390/ijms232012298 |
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