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Cathepsin S Inhibition Suppresses Experimental Systemic Lupus Erythematosus-Associated Pulmonary Arterial Remodeling

Patients with systemic lupus erythematosus (SLE) associated with pulmonary arterial hypnertension (PAH) receive targeted therapy for PAH to decrease pulmonary arterial systolic pressure and significantly prolong their survival. Cysteine cathepsin proteases play critical roles in the progression of c...

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Detalles Bibliográficos
Autores principales: Yen, Tzung-Hai, Ho, Wan-Jing, Yeh, Yung-Hsin, Lai, Ying-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603876/
https://www.ncbi.nlm.nih.gov/pubmed/36293172
http://dx.doi.org/10.3390/ijms232012316