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Oxidative stress alters transcript localization of disease-associated genes in the retinal pigment epithelium

PURPOSE: Nuclear retention is a mechanism whereby excess RNA transcripts are stored in the event that a cell needs to quickly respond to a stimulus; maintaining proper nuclear-to-cytoplasmic balance is important for cellular homeostasis and cell function. There are many mechanisms that are employed...

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Detalles Bibliográficos
Autores principales: Kaczynski, Tadeusz J., Au, Elizabeth D., Farkas, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603899/
https://www.ncbi.nlm.nih.gov/pubmed/36338668