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Sulforaphane recovers cone function in an Nrf2-dependent manner in middle-aged mice undergoing RPE oxidative stress

PURPOSE: Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables that has therapeutic efficacy in numerous animal models of human disease, including mouse models of retinal degeneration. However, despite dozens of clinical trials, the compound remains to be tested as a clinical t...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoping, Walton, Dorothy A., Plafker, Kendra S., Boulton, Michael E., Plafker, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603948/
https://www.ncbi.nlm.nih.gov/pubmed/36338670