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Sulforaphane recovers cone function in an Nrf2-dependent manner in middle-aged mice undergoing RPE oxidative stress
PURPOSE: Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables that has therapeutic efficacy in numerous animal models of human disease, including mouse models of retinal degeneration. However, despite dozens of clinical trials, the compound remains to be tested as a clinical t...
Autores principales: | Qi, Xiaoping, Walton, Dorothy A., Plafker, Kendra S., Boulton, Michael E., Plafker, Scott M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603948/ https://www.ncbi.nlm.nih.gov/pubmed/36338670 |
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