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Cabozantinib-Loaded PLGA Nanoparticles: A Potential Adjuvant Strategy for Surgically Resected High-Risk Non-Metastatic Renal Cell Carcinoma

Patients with high-risk non-metastatic renal cell carcinoma (RCC) are at risk of metastatic relapse following nephrectomy. Cabozantinib (CZ), a potent multitarget tyrosine kinase inhibitor, interferes with angiogenesis and immunosuppression associated with surgery-induced metastasis. Here, we explor...

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Detalles Bibliográficos
Autores principales: Lee, Hye Won, Seo, Hee Seung, Yeom, Seon-Yong, Kim, Se-Na, Kim, Cho Rim, Park, Dae-Hwan, Park, Wooram, Choy, Young Bin, Park, Chun Gwon, Seo, Seong Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604013/
https://www.ncbi.nlm.nih.gov/pubmed/36293494
http://dx.doi.org/10.3390/ijms232012634