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Complementary Dual Approach for In Silico Target Identification of Potential Pharmaceutical Compounds in Cystic Fibrosis

Cystic fibrosis is a genetic disease caused by mutation of the CFTR gene, which encodes a chloride and bicarbonate transporter in epithelial cells. Due to the vast range of geno- and phenotypes, it is difficult to find causative treatments; however, small-molecule therapeutics have been clinically a...

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Detalles Bibliográficos
Autores principales: Vinhoven, Liza, Stanke, Frauke, Hafkemeyer, Sylvia, Nietert, Manuel Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604016/
https://www.ncbi.nlm.nih.gov/pubmed/36293229
http://dx.doi.org/10.3390/ijms232012351