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Complementary Dual Approach for In Silico Target Identification of Potential Pharmaceutical Compounds in Cystic Fibrosis
Cystic fibrosis is a genetic disease caused by mutation of the CFTR gene, which encodes a chloride and bicarbonate transporter in epithelial cells. Due to the vast range of geno- and phenotypes, it is difficult to find causative treatments; however, small-molecule therapeutics have been clinically a...
Autores principales: | Vinhoven, Liza, Stanke, Frauke, Hafkemeyer, Sylvia, Nietert, Manuel Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604016/ https://www.ncbi.nlm.nih.gov/pubmed/36293229 http://dx.doi.org/10.3390/ijms232012351 |
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